Document Type
Case Report
Abstract
Background: CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory disease process primarily involving the pons and adjacent structures. Clinically, the patient may present with cerebellar signs such as dysarthria, gait ataxia and with cranial nerve palsies. It shows good response to steroids / immunosuppressive therapy. Pathologically, there is infiltration of T lymphocytes into the perivascular spaces of brainstem. The disease follows a relapsing and a remitting course and the earlier the treatment is started with high dose steroids and the more prolonged it is, the better the clinical outcome will be.
Recommended Citation
Salam, Abdul; Sana, Farah; Nazir, Rashed; Saeed, M. Azhar; Iqbal, Yasir; and Ahmad, Arsalan
(2014)
"Clippers (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids)–case report with neuroimaging,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 9:
Iss.
3, Article 8.
Available at:
https://ecommons.aku.edu/pjns/vol9/iss3/8
