Introduction of interferon b-1b in the therapeutic strategy against Multiple Sclerosis has resulted in a great amelioration of treatment in various terms. Relapse rates, delaying progression of the activity, improvement of imaging outcomes as well as reduction of disease activity itself consist great achievements against a pathological condition that challenged medical effectiveness throughout decades. Two recombinant human IFN-1a and an IFN-1b preparations have been proved effected and well tolerated. We reviewed the most important literature concerning pharmacodynamics, medical efficacy, tolerability and adverse effects of interferon-b usage. In parallel, despite the wide range of trials referring to INF-b treatment, we tried to categorize results of main trials in order to present our conclusions systematically
A, Evangelos; Ch. Syrmos, , Nikolaos; and Orologas, Anastasios
"Efficacy of interferon in multiple sclerosis,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 8
, Article 6.
Available at: http://ecommons.aku.edu/pjns/vol8/iss2/6