Efficacy of interferon in multiple sclerosis

Authors

Evangelos A, Neurological Clinic, Laboratory of Neuropathology, AHEPA Hospital
, Nikolaos Ch. Syrmos, Neurosurgery Clinic, AHEPA Hospital, School of Medicine, Aristotle’s University of Thessaloniki, Greece
Anastasios Orologas, Neurological Clinic, AHEPA Hospital, School of Medicine, Aristotle’s University of Thessaloniki, Greece

Document Type

Review Article

Abstract

Introduction of interferon b-1b in the therapeutic strategy against Multiple Sclerosis has resulted in a great amelioration of treatment in various terms. Relapse rates, delaying progression of the activity, improvement of imaging outcomes as well as reduction of disease activity itself consist great achievements against a pathological condition that challenged medical effectiveness throughout decades. Two recombinant human IFN-1a and an IFN-1b preparations have been proved effected and well tolerated. We reviewed the most important literature concerning pharmacodynamics, medical efficacy, tolerability and adverse effects of interferon-b usage. In parallel, despite the wide range of trials referring to INF-b treatment, we tried to categorize results of main trials in order to present our conclusions systematically

Recommended Citation

A, Evangelos; Ch. Syrmos, , Nikolaos; and Orologas, Anastasios (2013) "Efficacy of interferon in multiple sclerosis," Pakistan Journal of Neurological Sciences (PJNS): Vol. 8: Iss. 2, Article 6.
Available at: https://ecommons.aku.edu/pjns/vol8/iss2/6