Neuromyelitis optica (NMO) also known as Devic’s disease is an acute demyelinating disorder combined with optic neuritis and transverse myelitis.A 10 years old boy presented in the ER with the complaints of fever and back pain for past 10 days and inability to walk for 6-7 days. He had developed urinary retention and constipation for the past 5 days along with abdominal distension. There was also blurring of vision in the left eye with only light perception and rapid afferent papillary defect was present while the right eye was normal. The provisional diagnosis was Transverse myelitis vsNeuromyelitisoptica (NMO). CSF revealed TLC 4, protein 54mg/dl, glucose 66mg/dl. Oligoclonal bands were negative. There was raised CPK. Visual evoked potential (VEP) showed prolongation of P100 latency along with amplitude loss, in left eye.His MRI spine showed extensive involvement of the spinal cord especially the cervical cord and there was no involvement of the brain. Left eye had optic neuritis.He was treated with steroid pulse therapy and later Plasmapharesis and was discharged home on azathioprine with no motor deficit but the visual loss was irreversible
Jan, Dr.Farida; Shabir, Amber; and Ibrahim, Shahnaz
"Neuromyelitis optica (devic’s disease) in a 10 years old boy.,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 11
, Article 5.
Available at: http://ecommons.aku.edu/pjns/vol11/iss2/5