Marburg variant of multiple sclerosis (MS) is a highly aggressive, fulminant demyelinating disease with very high morbidity and mortality. Early diagnosis and aggressive management is vital to limit severe disability and improve the outcome. We present a case of 35 years old male who presented with rapidly progressive demyelinating illness, leading to bed bound status over the course of a month. He was treated aggressively with intravenous (IV) steroids, plasma exchange (PLEX) and Mitoxantrone (MTX), leading to a remarkable recovery.
Imtiaz, Sadia; Siddiqui, Maimoona; and MD, Arsalan Ahmad
"Marburg variant of multiple sclerosis; a diagnostic and therapeutic challenge,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 10
, Article 9.
Available at: http://ecommons.aku.edu/pjns/vol10/iss2/9