Paediatrics and Child Health
An eleven-year-old boy presented with one month's history of fever and weight loss. He was diagnosed with Acute Mycloid Leukemia (AML-M2). During treatment he developed recurrent infections with neutropenia requiring prolonged antibiotics and subsequently developed invasive aspergillosis. He was treated with amphotericin B and Voriconazole. This case shows the efficacy and safety of combined antifungal therapy, including voriconazole, for invasive aspergillosis complicating AML.
Journal of the Pakistan Medical Association
(2010). Successful management of invasive aspergillosis with voriconazole and amphoteracin B therapy in a patient with acute mycloid leukemia (AML-M2). Journal of the Pakistan Medical Association, 60(11), 977-9.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/25