The management of patients with residual masses following chemotherapy for advanced seminoma remains a difficult problem with no clear guidelines. While most patients with advanced seminoma achieve a complete or partial response with cisplatin based chemotherapy1, a significant number will reveal a residual mass on follow up CT scan or MR imaging2,3. Management options for post chemotherapy residual mass in a case of seminoma include close observation, radiation therapy and excisional surgery. While 80 to 85% of residual masses represent either fibrosis or necrotic tissue needing no further therapy, 10 to 15% may contain viable tumor which, if not recognized and effectively treated, may be lethal. A case of a stage II seminoma with post chemotherapy residual mass is presented and contemporary literature on this topic is reviewed.
Journal of the Pakistan Medical Association
Ahmad, N. A.,
Biyabani, S. R.,
(2002). Post-chemotherapy residual mass in stage IIC seminomatous testicular tumor. Journal of the Pakistan Medical Association, 83(12), 576-578.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_surg_urol/29