The human squamous cervical Carcinoma cell line, HOG-1, is responsive to Steroid hormones
Pathology and Microbiology
Growth of the human squamous cervical carcinoma cell line, HOG-1, was stimulated in response to oestradiol in serum-containing and chemically defined medium. The oestradiol-stimulated growth could be inhibited by 4-OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum-containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex-steroid hormones and suggest that endocrine therapies may be of benefit in this disease
International Journal of Cancer
White, J. O.,
Jones, R. N.,
Croxtall, J. D.,
Gleeson, R. P.,
Beesley, J. E.,
Soutter, W. P.
(1992). The human squamous cervical Carcinoma cell line, HOG-1, is responsive to Steroid hormones. International Journal of Cancer, 52(2), 247-251.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/315