Fluoroquinolone Resistance among Mycobacterium tuberculosis Strains from Karachi, Pakistan: Data from Community-Based Field Clinics
Document Type
Article
Department
Pathology and Microbiology
Abstract
A fluoroquinolone (FQ) resistance rate of 5.9% is reported in 205 Mycobacterium tuberculosis isolates from Patients presenting to field clinics in Karachi, Pakistan (2006 to 2009). FQ resistance among multidrug-resistant (MDR) strains was 11.1% (5/45), and it was 4.9% (5/103) in M. tuberculosis strains susceptible to all first-line agents. Spoligotyping of resistant strains did not show dominance of one strain type. Our data reflect considerable FQ-resistant M. tuberculosis isolates and the need to consider inclusion of FQ within first-line sensitivity testing in such settings.
Publication (Name of Journal)
Antimicrobial Agents and Chemotherapy
Recommended Citation
Rafiq, Y.,
Jabeen, K.,
Hasan, R.,
Jafri, S.,
Laiq, R.,
Malik, F.,
Mangi, R.,
Channa, A.,
Hasan, Z.
(2011). Fluoroquinolone Resistance among Mycobacterium tuberculosis Strains from Karachi, Pakistan: Data from Community-Based Field Clinics. Antimicrobial Agents and Chemotherapy, 55(2), 929-930.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/110