Pulmonary and Critical Care
Objective: To determine the six-minute walking distance (6MWD) for healthy Pakistanis, identify factors affecting 6MWD, compare published equations with the local data and derive an equation. Study Design: Cross-sectional study. Place and Duration of Study: Two medical institutes of Karachi, from January to May 2011. Methodology: Subjects between 15 and 65 years were prospectively enrolled after screening. A standardized 6MWT was administered. SpO2, HR, BP and dyspnoea scores were determined pre- and post-test. Results: Two hundred and eleven (71%) men and 85 (29%) women participated. Mean 6MWD was 469.88 Â± 101.24 m: men walked 502.35 Â± 92.21 m and women walked 389.28 Â± 74.29 m. On univariate analysis, gender, height, weight and age showed a significant relationship with the 6MWD. Gender and age were identified as independent factors in multiple regression analysis, and together explained 33% of the variance. The gender-specific prediction equations were: 6MWD (m) for men = 164.08 + (78.06*1) - (1.90*age in years) + (1.95*height in cms) 6MWD (m) for women = 164.08 - (1.90*age in years) + (1.95*height in cms). Conclusion: 6MWDs among the volunteer subjects were shorter than predicted by reference equations in literature. Height, gender and weight combined explained 33% of the variance. The moderate over-estimation of the 6MWD in Pakistani subject. The proposed equation gives predicted (mean) 6MWDs for adult Pakistani naÃ¯ve to the test when employing standardized protocol.
Journal of the College of Physicians and Surgeons Pakistan
Rao, N. A.,
Haque, A. S.,
Zubairi, A. B.,
(2013). Six-Minute Walk Test Performance in Healthy Adult Pakistani Volunteers. Journal of the College of Physicians and Surgeons Pakistan, 23(10), 720-725.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_med_pulm_critcare/23