Title

Default during TB diagnosis: quantifying the problem

Document Type

Article

Department

Pulmonary and Critical Care

Abstract

Objectives:To quantify default during diagnosis in TB suspects and in smear-positive cases, to investigate sex differences in default during diagnosis, in all of Pakistan.

Methods:

Data from laboratory registers were collected on 12 216 suspects in nine districts over the period July-September 2008. Results:A total of 1573 TB suspects (12.9%, 95% CI = 12.3-13.5) dropped out of the diagnostic process after initial sputum submission. A total of 2058 smear-positive cases were detected, and of these 107 (5.2%, 95% CI = 4.2-6.2) defaulted during diagnosis and therefore could not be started on treatment. Male suspects defaulted slightly more frequently than female suspects (P = 0.0268).

Conclusion:

Default during diagnosis is a frequent occurrence in Pakistan that should be monitored and addressed by TB control programs.

Publication

Tropical Medicine & International Health