Document Type
Article
Department
Biological and Biomedical Sciences
Abstract
Acanthamoeba is a free-living protist pathogen, capable of causing a blinding keratitis and fatal granulomatous encephalitis. The factors that contribute to Acanthamoeba infections include parasite biology, genetic diversity, environmental spread and host susceptibility, and are highlighted together with potential therapeutic and preventative measures. The use of Acanthamoeba in the study of cellular differentiation mechanisms, motility and phagocytosis, bacterial pathogenesis and evolutionary processes makes it an attractive model organism. There is a significant emphasis on Acanthamoeba as a Trojan horse of other microbes including viral, bacterial, protists and yeast pathogens.
Publication (Name of Journal)
Parasites & Vectors
Recommended Citation
Siddiqui, R.,
Khan, N.
(2012). Biology and pathogenesis of Acanthamoeba.. Parasites & Vectors, 5, 6.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_bbs/47