Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population
Biological and Biomedical Sciences
An association study of IL-1 beta -511C/T and IL-1 RN 86 bp VNTR polymorphisms with essential hypertension was carried out in a sample population of 500 Pakistani Pathan subjects selected randomly, comprising groups of 235 subjects with hypertension and 265 controls. The distribution of both genotypes and alleles was not statistically different in cases and controls. In conclusion, IL-1 beta -511C/T and IL-1 RN 86 bp VNTR do not contribute to the aetiology of essential hypertension in the Pakistani Pathan population investigated here.
Journal of Human Hypertension
(2008). Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population. Journal of Human Hypertension, 22(1), 60-62.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_bbs/42