Ultrathinlayer SDS-polyacrylamide gradient gel electrophoresis of cerebrospinal fluid proteins

Document Type

Article

Department

Biological and Biomedical Sciences

Abstract

Alkaline phosphatase is widely distributed within and on the surface of mammalian cells and
exists in a number of tissue-specific isoenzyme forms [11. These isoenzymes exhibit varying
degrees of inhibition by amino acids (eg L-phenylalanine) in the concentration range 10-2-
10-3 M [2]. Little is known about the mechanism of phenylalanine inhibition except that it is
non-competitive and takes place at a site distant from the active centre.

Publication (Name of Journal)

Biochemical Society Transactions

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