Biological and Biomedical Sciences
The present study was carried out to evaluate the anthelmintic activity of Terminalia arjuna (Roxb.) bark locally used as an anthelmintic. Lethal median concentration (LC50 values) of methanolic extract of T. arjuna bark in egg hatch and larval development tests against Haemonchus contortus ova and larva were found to be 645.65 and 467.74 μg mL-1, respectively. Inadult motility assay, efficacy of the extract was evident by the mortality of H. contortus at different hours post exposure. Invivo results revealed maximum (87.3%) egg count percent reduction (ECR) in sheep treated with crude methanolic extract @ 3 g kg-1 body weight on day 11 post-treatment (PT). The data revealed dose-dependent anthelmintic activity both in the invitro and in vivo studies, thus justifying its use in the traditional medicine system of Pakistan
International Journal of Agriculture & Biology
Bachaya, H. A.,
Khan, M. N.,
Gilani, A. H.,
(2009). In vitro and in vivo anthelmintic activity of terminalia arjuna bark. International Journal of Agriculture & Biology, 11, 273-278.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_bbs/242