Next generation of non-mammalian blood-brain barrier models to study parasitic infections of the central nervous system.

Document Type

Article

Department

Biological and Biomedical Sciences

Abstract

Transmigration of neuropathogens across the blood-brain barrier is a key step in the development of central nervous system infections, making it a prime target for drug development. The ability of neuropathogens to traverse the blood-brain barrier continues to inspire researchers to understand the specific strategies and molecular mechanisms that allow them to enter the brain. The availability of models of the blood-brain barrier that closely mimic the situation in vivo offers unprecedented opportunities for the development of novel therapeutics.

Publication (Name of Journal)

Virulence

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