Biological and Biomedical Sciences
Migraine is a very common type of headache. With a prevalence of 10-12%, migraine ranks 19th among diseases causing worldwide morbidity. Number of studies have shown a high prevalence of patent foramen ovale (PFO) in patients with migraine, especially migraine with aura. The right to left shunting of blood in a PFO could serve as a conduit for chemicals that would exert a trigger effect on hyper excitable neurons leading to the development of migraine. Furthermore patients with PFO and migraine also show a marked improvement in their symptoms after percutaneous closure of the PFO. This review is a close look at this association and also explores whether subsequent closure of the shunt can be looked upon as a viable treatment option.
Journal of the Pakistan Medical Association
(2008). Migraine and patent foramen ovale: exploring the association and a possible treatment option. Journal of the Pakistan Medical Association, 58(8), 453-5.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_bbs/10