Oral squamous cell carcinoma in human immunodeficiency virus positive patients: clinicopathological audit
Pathology (East Africa)
Background: Most human immunodeficiency virus positive patients now have a longer life expectancy, with the advent of highly active antiretroviral therapy. However, they are now at increased risk of developing a malignancy during their lives.
Aim: To investigate the age at which oral squamous cell carcinoma presents in patients infected with human immunodeficiency virus.
Study design: Prospective, clinicohistopathological audit of patients infected with human immunodeficiency virus.
Results: Of 200 human immunodeficiency virus positive patients, 16 (8 per cent) presented with oral squamous cell carcinoma (nine women and seven men; age range 18–43 years, mean age 31.7 years). The majority of patients (62.5 per cent) had stage III and IV disease (tumour-node-metastasis staging). There was a predilection for poorly differentiated oral squamous cell carcinoma (using Broder’s histopathological classification).
Conclusion: Oral squamous cell carcinoma associated with human immunodeficiency virus infection appears to present at a relatively young age.
The Journal of Laryngology & Otology
Butt, F. M.,
Chindia, M. L.,
(2012). Oral squamous cell carcinoma in human immunodeficiency virus positive patients: clinicopathological audit. The Journal of Laryngology & Otology, 126, 276-278.
Available at: http://ecommons.aku.edu/eastafrica_fhs_mc_pathol/29
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