Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias?

Authors

Faizel Osman, University Hospital Coventry
Suman Kundu, University of Leicester
Jiun Tuan, University of Leicester
Jeilan Mohamed, Aga Khan UniversityFollow
Peter J. Stafford, University of Leicester
G. Andre' Ng, University of Leicester

Document Type

Article

Department

Internal Medicine (East Africa)

Abstract

Catheter ablation is increasingly used to treat patients with atrial fibrillation (AF). Ablation of ganglionic plexi is often performed to reduce vagal innervation and has been shown to confer a better long-term outcome in terms of AF recurrence. We report a case of a patient having AF ablation with a profound vagal response, suggesting ganglionic plexus ablation, who subsequently developed ventricular fibrillation after programmed ventricular stimulation. Reduced vagal modulation is known to predispose to ventricular arrhythmias and vagal denervation following AF ablation may predispose to ventricular arrhythmias and requires further study.

Comments

This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Indian Pacing and Electrophysiology Journal

Recommended Citation

Osman, F., Kundu, S., Tuan, J., Mohamed, J., Stafford, P. J., Andre' Ng, G. (2010). Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias?. Indian Pacing and Electrophysiology Journal, 10(2), 104-107.
Available at: https://ecommons.aku.edu/eastafrica_fhs_mc_intern_med/68