Cytological diagnosis of typical carcinoid on bronchoscopic brush smears in an HIV-positive patient
Pathology (East Africa); Internal Medicine (East Africa)
We report a case of typical carcinoid of the lung in a 60-year-old human immunodeficiency virus (HIV)-positive man diagnosed on brush cytology smears. Bronchial carcinoids are rare tumors, accounting for 1% to 2% of all lung tumors. Although the exact incidence in HIV-infected individuals is not known, the paucity of their documentation in the literature indicates that they may be equally rare. Cytological diagnosis on brush smears is rarely documented as the tumor is covered with mucosa and cellular yield is often not good. In this case, bronchial brushings showed distinctive cytological features of typical carcinoid. The awareness of its characteristic cytological features and differential diagnosis is required for an accurate diagnosis. Clinical awareness that non-acquired immunodeficiency syndrome (AIDS)-defining cancers can also occur in HIV-infected individuals in the context of the prolonged survival in the antiretroviral era equally important. This case emphasizes the clinical importance of a broad differential diagnosis for lung lesions in HIV-positive patients.
Journal of Cytology
(2011). Cytological diagnosis of typical carcinoid on bronchoscopic brush smears in an HIV-positive patient. Journal of Cytology, 28(3), 134-137.
Available at: http://ecommons.aku.edu/eastafrica_fhs_mc_intern_med/15
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