Event Title

Impact of nutritional assessment and intervention on the nutritional status of bone marrow transplant patients

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Introduction: Bone marrow transplantation (BMT) includes grafting with allogeneic or autologous stem cells derived from bone marrow, peripheral blood and cord blood. An autologous involves receiving patients own cells where as an allogeneic bone marrow transplant involves receiving very high-doses of chemotherapy and/or radiation therapy, followed by the infusion donor’s bone marrow or peripheral stem cells. The objective of this study was to assess nutritional status pre-transplant and the impact of aggressive post transplant nutritional intervention on BMT subjects. Methods: This 5 years study was conducted from 2008 to 2013 and included 73 patients whose nutritional status was assessed. This included anthropometric measurements, biochemical data and diet history evaluation. Results: Total number of BMT patient seen were 73 with 58 % allogeneic 42 % autologous (BMT), BMI was found to be low in both groups (<19). The incidence of mucositis was significantly higher (81 %) in the autologous group than in the allogeneic group ( 67 %, P<0.005). Serum albumin was found low in allogeneic transplant patients (56%) <2.5). Early nutritional interventions included nutritional screening and assessment with aggressive post-transplant feeding regimes before onset of BMT side effects. The requirement for TPN was reduced in 38% patient with early nutritional interventions.

Conclusion: Nutritional assessment is an important consideration in both groups. Further studies are needed to focus on specific dietary management.

Keywords: Bone marrow, Allogeneic transplant, autologous transplant, chemotherapy

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Feb 26th, 10:30 AM

Impact of nutritional assessment and intervention on the nutritional status of bone marrow transplant patients

Auditorium Pond Side

Introduction: Bone marrow transplantation (BMT) includes grafting with allogeneic or autologous stem cells derived from bone marrow, peripheral blood and cord blood. An autologous involves receiving patients own cells where as an allogeneic bone marrow transplant involves receiving very high-doses of chemotherapy and/or radiation therapy, followed by the infusion donor’s bone marrow or peripheral stem cells. The objective of this study was to assess nutritional status pre-transplant and the impact of aggressive post transplant nutritional intervention on BMT subjects. Methods: This 5 years study was conducted from 2008 to 2013 and included 73 patients whose nutritional status was assessed. This included anthropometric measurements, biochemical data and diet history evaluation. Results: Total number of BMT patient seen were 73 with 58 % allogeneic 42 % autologous (BMT), BMI was found to be low in both groups (<19). The incidence of mucositis was significantly higher (81 %) in the autologous group than in the allogeneic group ( 67 %, P<0.005). Serum albumin was found low in allogeneic transplant patients (56%) <2.5). Early nutritional interventions included nutritional screening and assessment with aggressive post-transplant feeding regimes before onset of BMT side effects. The requirement for TPN was reduced in 38% patient with early nutritional interventions.

Conclusion: Nutritional assessment is an important consideration in both groups. Further studies are needed to focus on specific dietary management.

Keywords: Bone marrow, Allogeneic transplant, autologous transplant, chemotherapy