Event Title

Frequency of Periprocedural Myocardial Infarction in Elective Coronary Angioplasty

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Background: Cardiovascular disease is a leading cause of death worldwide. Besides risk factors modification and optimal medical therapy, Coronary angioplasty is one of the main stream line parts of the management protocol in coronary artery disease. Periprocedural myocardial infarction (PMI) is animportant procedure related complication during coronary angioplasty, which is associated with increased mortality and present in 24% elective coronary angioplasty as per literature review. Study is warranted to determine the incidence of PMI in patients presented to tertiary care hospital.

Objective: To determine the frequency of periprocedural myocardial infarction in patients with stable coronary artery disease undergoing elective coronary angioplasty.

Methods: This was a cross sectional study, conducted over period of 6 months in section of cardiology the Aga Khan University hospital. Patients were prospectively enrolled from the in-patients and CK-MB level were measured immediately and 6 hours after angioplasty. Significance of differences in mean CK-MB level over time was tested by paired t-test. P value ≤ 0.05 was considered to be significant.

Results: Of the total 110 patients, there were 90 (81.8%) male and 20 (18.2%) female. Mean ± standard deviation age of the study population was 59.8± 9.47. Overall PMI was present in 22/110 (20%) patients. PMI was present in males and females 17 (77.3%), 5 (22.7%) respectively. Out of total 22 patients 4 (18.2%) were under 50 years and 18 (81.8%) were over 50 years. Mean ± standard deviation CK-MB level immediately and 6 hours after coronary angioplasty was 4.09 ± 6.49 and 9.13 ± 14.47 respectively.

Conclusion: Frequency of periprocedural myocardial infarction is comparable in this study to that observed internationally. Further studies are required to confirm these findings in our population.

Keywords: Coronary angioplasty, periprocedural myocardial infarction, Creatine Kinase myocardial band

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Feb 26th, 10:30 AM

Frequency of Periprocedural Myocardial Infarction in Elective Coronary Angioplasty

Auditorium Pond Side

Background: Cardiovascular disease is a leading cause of death worldwide. Besides risk factors modification and optimal medical therapy, Coronary angioplasty is one of the main stream line parts of the management protocol in coronary artery disease. Periprocedural myocardial infarction (PMI) is animportant procedure related complication during coronary angioplasty, which is associated with increased mortality and present in 24% elective coronary angioplasty as per literature review. Study is warranted to determine the incidence of PMI in patients presented to tertiary care hospital.

Objective: To determine the frequency of periprocedural myocardial infarction in patients with stable coronary artery disease undergoing elective coronary angioplasty.

Methods: This was a cross sectional study, conducted over period of 6 months in section of cardiology the Aga Khan University hospital. Patients were prospectively enrolled from the in-patients and CK-MB level were measured immediately and 6 hours after angioplasty. Significance of differences in mean CK-MB level over time was tested by paired t-test. P value ≤ 0.05 was considered to be significant.

Results: Of the total 110 patients, there were 90 (81.8%) male and 20 (18.2%) female. Mean ± standard deviation age of the study population was 59.8± 9.47. Overall PMI was present in 22/110 (20%) patients. PMI was present in males and females 17 (77.3%), 5 (22.7%) respectively. Out of total 22 patients 4 (18.2%) were under 50 years and 18 (81.8%) were over 50 years. Mean ± standard deviation CK-MB level immediately and 6 hours after coronary angioplasty was 4.09 ± 6.49 and 9.13 ± 14.47 respectively.

Conclusion: Frequency of periprocedural myocardial infarction is comparable in this study to that observed internationally. Further studies are required to confirm these findings in our population.

Keywords: Coronary angioplasty, periprocedural myocardial infarction, Creatine Kinase myocardial band