Event Title

Comparison of HDL-raising efficacy of Pakistani and American almonds in coronary artery disease patients with sub-optimal HDL

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Background and Objective: More than 70% of Coronary Artery Disease (CAD) patients in our population, despite of having well-managed LDL have sub-optimal serum HDL levels. We therefore plan to compare the HDL-raising effect of Pakistani and American almonds on CAD patients with optimal LDL and sub-optimal HDL levels. Study Design: A total of sixty CAD patients with LDL < 100 md/dl and HDL < 40 mg/dl male and < 50 mg/dl female, were recruited from the Aga Khan University Hospital. Arm 1 (Control) was not given almonds during the study, whereas arm 2 and 3 received Pakistani and American almonds respectively. 10 grams almond/day were to be consumed after overnight soaking and removal of skin for how long?six weeks. Lipid profiling was conducted atafter six weeks. Preliminary

Results: A significant) increase of 16.8% and 14.8% (p < 0.05) was obtained in serum HDL after 6 weeks consumption of f Pakistani and American almonds, respectively. The difference among the two almond varieties was not significant. Triglyceride, total cholesterol, LDL, VLDL, body weight and blood pressure were not significantly affected.

Conclusion/Recommendation: Ten grams of overnight soaked and peeled almonds (of either variety) potentially improves serum HDL in CAD patients with sub-optimal HDL.

Keywords: Almond, Coronary Artery Disease, HDL, Pakistan

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Feb 26th, 10:30 AM

Comparison of HDL-raising efficacy of Pakistani and American almonds in coronary artery disease patients with sub-optimal HDL

Auditorium Pond Side

Background and Objective: More than 70% of Coronary Artery Disease (CAD) patients in our population, despite of having well-managed LDL have sub-optimal serum HDL levels. We therefore plan to compare the HDL-raising effect of Pakistani and American almonds on CAD patients with optimal LDL and sub-optimal HDL levels. Study Design: A total of sixty CAD patients with LDL < 100 md/dl and HDL < 40 mg/dl male and < 50 mg/dl female, were recruited from the Aga Khan University Hospital. Arm 1 (Control) was not given almonds during the study, whereas arm 2 and 3 received Pakistani and American almonds respectively. 10 grams almond/day were to be consumed after overnight soaking and removal of skin for how long?six weeks. Lipid profiling was conducted atafter six weeks. Preliminary

Results: A significant) increase of 16.8% and 14.8% (p < 0.05) was obtained in serum HDL after 6 weeks consumption of f Pakistani and American almonds, respectively. The difference among the two almond varieties was not significant. Triglyceride, total cholesterol, LDL, VLDL, body weight and blood pressure were not significantly affected.

Conclusion/Recommendation: Ten grams of overnight soaked and peeled almonds (of either variety) potentially improves serum HDL in CAD patients with sub-optimal HDL.

Keywords: Almond, Coronary Artery Disease, HDL, Pakistan