Event Title

Atheroprotective effects of dietary mixture (lemon, garlic, ginger, honey & apple vinegar) in cholesterol FED rabbits

Presenter Information

Erum Naseem, University of Karachi

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Introduction: Coronary artery diseases are the leading cause of mortality, worldwide. Dietary modifications are an effective tool of primary prevention therapies. Research studies are trying to identify the combination of nutrients to decrease or prevent future risks for cardiovascular diseases without producing any harmful side effects. Current study is planned to investigate the effectiveness of a mixture of culinary spices (garlic, ginger), fruits (lemon, apple vinegar) and honey on diet induced dyslipidemia in experimental animals.

Material and Methods: Total sixteen rabbits of either sex were acclimatized for two weeks and divided into two groups. Group I animals received normal diet and serve as control. Group II were administered with hyperlipidemic diet (1g butter fat/100g of daily diet) along with normal rabbit chow for one month. These hyperlipidemic animals were then treated with the prepared mixture for two weeks. At the end of experimental period, blood specimens were collected and assayed for plasma levels of lipids and glucose.

Results: Two weeks oral administration of dietary mixture significantly reduces the blood lipid profile and glucose levels in hyperlipidemic animals.

Conclusion: The proposed mixture of diet produces antihyperlipidemic, and anti-diabetic effects in experimental animal models of hyperlipidemia. As primary prevention therapy, this mixture can be used effectively to treat high risk cardiac patients.

Keywords: coronary artery disease, dietary mixture, rabbits, atherosclerosis

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Feb 26th, 10:30 AM

Atheroprotective effects of dietary mixture (lemon, garlic, ginger, honey & apple vinegar) in cholesterol FED rabbits

Auditorium Pond Side

Introduction: Coronary artery diseases are the leading cause of mortality, worldwide. Dietary modifications are an effective tool of primary prevention therapies. Research studies are trying to identify the combination of nutrients to decrease or prevent future risks for cardiovascular diseases without producing any harmful side effects. Current study is planned to investigate the effectiveness of a mixture of culinary spices (garlic, ginger), fruits (lemon, apple vinegar) and honey on diet induced dyslipidemia in experimental animals.

Material and Methods: Total sixteen rabbits of either sex were acclimatized for two weeks and divided into two groups. Group I animals received normal diet and serve as control. Group II were administered with hyperlipidemic diet (1g butter fat/100g of daily diet) along with normal rabbit chow for one month. These hyperlipidemic animals were then treated with the prepared mixture for two weeks. At the end of experimental period, blood specimens were collected and assayed for plasma levels of lipids and glucose.

Results: Two weeks oral administration of dietary mixture significantly reduces the blood lipid profile and glucose levels in hyperlipidemic animals.

Conclusion: The proposed mixture of diet produces antihyperlipidemic, and anti-diabetic effects in experimental animal models of hyperlipidemia. As primary prevention therapy, this mixture can be used effectively to treat high risk cardiac patients.

Keywords: coronary artery disease, dietary mixture, rabbits, atherosclerosis