Event Title

Validation study of the mini-mental state examination in an Urdu language for Pakistani population

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Objective: This study was conducted primarily to validate and determine the optimal cutoff score in the diagnosis of dementia among Pakistani’s and study the effects of gender and education on the MMSE performance in our population.

Methods: Four hundred participants took part in the study. Of these, 100 were dementia patients and 300 were non-dementia participants. Patient with dementia recruited from five major hospitals from Pakistan. The MMSE was translated into Urdu. In order to determine the optimal cutoff scores, the sensitivity and specificity were calculated.

Results: There were 61 men and 39 women in dementia group and 225 men and 75 women in the control group. The mean score of Urdu MMSE were lower in patients with dementia 18.5 ± 5.6 (range 0-30) as compared to the controls 26.8 ± 2.6 (range 7-30). This difference between groups was statistically significant (p<0.001). Subjects with illiterate and up to 10 grades had significantly lower mean scores in patients with dementia group compare to those with higher education (p<0.001). Educational based MMSE score below 15 yielded perfect sensitivity and specificity for the diagnosis of dementia.

Conclusions:These finding confirm the influence of level of education on MMSE score and education stratified cutoff scores should be used while screening for cognitive impairment in this population

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Feb 26th, 10:30 AM

Validation study of the mini-mental state examination in an Urdu language for Pakistani population

Auditorium Pond Side

Objective: This study was conducted primarily to validate and determine the optimal cutoff score in the diagnosis of dementia among Pakistani’s and study the effects of gender and education on the MMSE performance in our population.

Methods: Four hundred participants took part in the study. Of these, 100 were dementia patients and 300 were non-dementia participants. Patient with dementia recruited from five major hospitals from Pakistan. The MMSE was translated into Urdu. In order to determine the optimal cutoff scores, the sensitivity and specificity were calculated.

Results: There were 61 men and 39 women in dementia group and 225 men and 75 women in the control group. The mean score of Urdu MMSE were lower in patients with dementia 18.5 ± 5.6 (range 0-30) as compared to the controls 26.8 ± 2.6 (range 7-30). This difference between groups was statistically significant (p<0.001). Subjects with illiterate and up to 10 grades had significantly lower mean scores in patients with dementia group compare to those with higher education (p<0.001). Educational based MMSE score below 15 yielded perfect sensitivity and specificity for the diagnosis of dementia.

Conclusions:These finding confirm the influence of level of education on MMSE score and education stratified cutoff scores should be used while screening for cognitive impairment in this population