Event Title

Prevalence of diabetic retinopathy amongst type-2 diabetic population in Pakistan (vision)

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Aims: Diabetic retinopathy (DR) is the principal cause of impaired vision in patients between 25 and 74 years of age. A vast majority of patients who develop DR have no ophthalmology symptoms until the very advanced stages. Pilot studies conducted in Pakistan estimate the prevalence of DR to be between 26-33 %. VISION is the first national study to assemble data on prevalence of DR in T2DM patients in Pakistan

Methods: This cross sectional study was conducted in nine cities across Pakistan from July 2009 -April 2010. Consecutive patients were recruited from 25 GP clinics. Patients were examined for DR by ophthalmologists using Welchallyn® ophthalmoscope. RBS levels were measured using J&Js OneTouch® glucometers and HbA1c was performed at the centralized lab. Results: Two hundred and twenty three patients were recruited. Analysis was based on evaluation of 202 patients (46.0% females). Mean age was 52.9 (sd ± 10.5) years, BMI 28.6 (sd ± 8.9) kg/m2. SBP 133.5 (sd ± 17.4) mmHg, DBP 86.1 (sd ± 9.6) mmHg, RBS 219.2 (sd ± 82.4) mg/dL and HbA1c of 8.9 (sd ± 2.5) %. Mean duration of T2DM was 8.8 (sd ± 5.1) years. On 10 gm monofilament examination neuropathy was detected in 59.9% patients and nephropathy was reported by 6.4% patients. Seventy seven percent of the patients had never been assessed for DR. The prevalence of DR in this population was 56.9% (C.I 50.1% - 63.3%). Seventy five percent of patients had HbA1c >7%. DR was detected across all levels of HbA1c. Fifty four percent of all the diabetic patients had uncontrolled HTN (SBP >130 mmHg and DBP >80 mmHg). Uncontrolled HTN and HbA1c > 7% coexisted in 41% of patients. The three common risk factors reported by the patients were hypertension, sedentary lifestyle and metabolic syndrome.

Conclusions: The prevalence of DR in this study population was high (57%).This progressive condition requires a timely and cost-effective management. Diabetic patients should be made aware of the importance of regular eye examination by primary care physician.

Keywords: Diabetic Retinopathy, Prevalence, T2DM, Pakistan

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Feb 26th, 10:30 AM

Prevalence of diabetic retinopathy amongst type-2 diabetic population in Pakistan (vision)

Auditorium Pond Side

Aims: Diabetic retinopathy (DR) is the principal cause of impaired vision in patients between 25 and 74 years of age. A vast majority of patients who develop DR have no ophthalmology symptoms until the very advanced stages. Pilot studies conducted in Pakistan estimate the prevalence of DR to be between 26-33 %. VISION is the first national study to assemble data on prevalence of DR in T2DM patients in Pakistan

Methods: This cross sectional study was conducted in nine cities across Pakistan from July 2009 -April 2010. Consecutive patients were recruited from 25 GP clinics. Patients were examined for DR by ophthalmologists using Welchallyn® ophthalmoscope. RBS levels were measured using J&Js OneTouch® glucometers and HbA1c was performed at the centralized lab. Results: Two hundred and twenty three patients were recruited. Analysis was based on evaluation of 202 patients (46.0% females). Mean age was 52.9 (sd ± 10.5) years, BMI 28.6 (sd ± 8.9) kg/m2. SBP 133.5 (sd ± 17.4) mmHg, DBP 86.1 (sd ± 9.6) mmHg, RBS 219.2 (sd ± 82.4) mg/dL and HbA1c of 8.9 (sd ± 2.5) %. Mean duration of T2DM was 8.8 (sd ± 5.1) years. On 10 gm monofilament examination neuropathy was detected in 59.9% patients and nephropathy was reported by 6.4% patients. Seventy seven percent of the patients had never been assessed for DR. The prevalence of DR in this population was 56.9% (C.I 50.1% - 63.3%). Seventy five percent of patients had HbA1c >7%. DR was detected across all levels of HbA1c. Fifty four percent of all the diabetic patients had uncontrolled HTN (SBP >130 mmHg and DBP >80 mmHg). Uncontrolled HTN and HbA1c > 7% coexisted in 41% of patients. The three common risk factors reported by the patients were hypertension, sedentary lifestyle and metabolic syndrome.

Conclusions: The prevalence of DR in this study population was high (57%).This progressive condition requires a timely and cost-effective management. Diabetic patients should be made aware of the importance of regular eye examination by primary care physician.

Keywords: Diabetic Retinopathy, Prevalence, T2DM, Pakistan