Event Title

Preoperative C reactive protein a predictor of duration of ICU stay

Location

Auditorium Pond Side

Start Date

26-2-2014 10:30 AM

Abstract

Elevated CRP is associated not only with an increased risk for cardiovascular disease but also for increased events of morbidity and mortality in patients with established coronary artery or cerebrovascular disease. Whether elevate CRP further increases the morbidity and mortality in patients undergoing coronary artery bypass grafting on cardiopulmonary bypass (CPB) remains unclear. This study aimed to evaluate raised CRP as the independent risk factor for prolong duration of ICU stay following coronary artery bypass grafting (CABG) METHODS AND RESULTS: Accordingly, we conducted a prospective observational study with pre-operative measurement of plasma CRP levels in consecutive patients undergoing coronary artery bypass grafting on CPB. Patients with preoperative CRP level more than 5mg/l were enrolled in studied .The association of pre-operative plasma CRP levels with post-operative duration of ICU stay and morbidity and mortality was evaluated. Elevated CRP levels (>5 mg/L) was found to have significant association with a prolong ICU stay (OR 3.00 95%CI 1.3550-6.641) and major morbidities like psychosis (OR2.73, 95%CI1.4-5.0) and acute renal failure (OR 3.58 ,95%CI1.12-11.4). CONCLUSION: Elevated pre-operative CRP level is independently associated with increased morbidity particularly in patients undergoing CABG..

Keywords: CRP; C reactive protein, CABG; Coronary artery bypass grafting, ICU; Intensive care unit, CPB; Cardiopulmonary bypass

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Feb 26th, 10:30 AM

Preoperative C reactive protein a predictor of duration of ICU stay

Auditorium Pond Side

Elevated CRP is associated not only with an increased risk for cardiovascular disease but also for increased events of morbidity and mortality in patients with established coronary artery or cerebrovascular disease. Whether elevate CRP further increases the morbidity and mortality in patients undergoing coronary artery bypass grafting on cardiopulmonary bypass (CPB) remains unclear. This study aimed to evaluate raised CRP as the independent risk factor for prolong duration of ICU stay following coronary artery bypass grafting (CABG) METHODS AND RESULTS: Accordingly, we conducted a prospective observational study with pre-operative measurement of plasma CRP levels in consecutive patients undergoing coronary artery bypass grafting on CPB. Patients with preoperative CRP level more than 5mg/l were enrolled in studied .The association of pre-operative plasma CRP levels with post-operative duration of ICU stay and morbidity and mortality was evaluated. Elevated CRP levels (>5 mg/L) was found to have significant association with a prolong ICU stay (OR 3.00 95%CI 1.3550-6.641) and major morbidities like psychosis (OR2.73, 95%CI1.4-5.0) and acute renal failure (OR 3.58 ,95%CI1.12-11.4). CONCLUSION: Elevated pre-operative CRP level is independently associated with increased morbidity particularly in patients undergoing CABG..

Keywords: CRP; C reactive protein, CABG; Coronary artery bypass grafting, ICU; Intensive care unit, CPB; Cardiopulmonary bypass